Toxic epidermal necrosis
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call craiceann caractar de Toxic epidermal necrosis
References
Tha Stevens-Johnson Syndrome (SJS) agus Toxic Epidermal Necrolysis (TEN) nan suidheachaidhean tearc far a bheil an craiceann a’ faighinn eòlas air necrosis farsaing agus rùsgadh. A thaobh làimhseachadh, tha cyclosporine air leth èifeachdach airson SJS, fhad ‘s a tha measgachadh de immunoglobulin intravenous (IVIg) agus corticosteroids ag obair as fheàrr airson cùisean SJS agus TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
Tha Toxic epidermal necrolysis (TEN) na dhroch ath-bhualadh craiceann air adhbhrachadh le cuid de chungaidh-leigheis agus gnìomhachd an t-siostam dìon, a’ leantainn gu sgaradh mòr den chòmhdach craiceann a-muigh (epidermis) , a ’toirt buaidh air còrr air 30% de uachdar na bodhaig. Tha ìre bàsmhorachd TEN de chòrr air 20%, gu tric mar thoradh air galairean agus duilgheadasan anail. Faodaidh stad a chur air a 'chungaidh-leigheis a tha ag adhbhrachadh an ath-fhreagairt, a' toirt seachad cùram taiceil, agus a 'cleachdadh leigheasan a bharrachd an toradh nas fheàrr. Tha sgrùdaidhean o chionn ghoirid air sealltainn gum faod drogaichean leithid cyclosporine, luchd-dìon factar necrosis tumhair, agus measgachadh de globulin dìonach intravenous agus corticosteroids a bhith cuideachail, stèidhichte air deuchainnean fo smachd air thuaiream agus mion-sgrùdaidhean air ioma-sgrùdaidhean.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
Recent Advances: There is improved understanding of pain and morbidity with regard to the type and frequency of dressing changes. More modern dressings, such as nanocrystalline, are currently favored as they may be kept in situ for longer periods. The most recent evidence on systemic agents, such as corticosteroids and cyclosporine, and novel treatments, are also discussed.
Is e an adhbhar as cumanta cungaidhean sònraichte leithid lamotrigine, carbamazepine, allopurinol, antibiotaicean sulfonamide, agus nevirapine. Am measg nam factaran cunnairt tha HIV agus lupus erythematosus siostaim. Mar as trice bidh làimhseachadh a’ tachairt san ospadal leithid ann an aonad losgaidh no aonad cùram dian.
○ làimhseachadh
Is e fìor ghalar a tha seo, mar sin ma tha buaidh air do bhilean no do bheul no ma dh’ fhàsas do chraiceann sèididh, faic an dotair agad cho luath ‘s a ghabhas.
Bu chòir stad a chur air drogaichean amharasach. (me antibiotics, drogaichean neo-steroidal anti-inflammatory)